At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

API & Drug Susbstance Operations - Supervisor - B5

Summary

The API & Drug Substance Operations Supervisor leads the day-to-day execution and continual improvement of manufacturing operations in a highly regulated environment, owning process performance and escalation pathways across API production. This role centers on maintaining safe, compliant operations by monitoring process alarms and responding to adverse events per established procedures, while serving as the expert consult for novel or unprecedented manufacturing challenges. It requires diagnosing and troubleshooting both routine and complex issues to restore and sustain production, with a focus on quality, compliance, and proactive problem solving. The Supervisor also guides teams in applying production management best practices to minimize recurrence and protect the integrity of the manufacturing process.

Key Responsibilities

• Lead routine safety and quality walkthroughs of the production area to identify hazards and compliance gaps.

• Monitor and control manufacturing process parameters to maintain product quality within defined specifications.

• Lead investigations into manufacturing deviations and recommend process adjustments based on findings.

• Manage risks by proactively identifying potential compliance or quality issues and implementing mitigation strategies.

• Troubleshoot routine and complex manufacturing issues to restore operations and prevent recurrence.

• Provide expert consultation for novel or unprecedented manufacturing challenges requiring specialized knowledge.

• Monitor process alarms and respond to adverse events per established procedures to maintain safe and compliant operations.

• Lead small-scale local projects to improve manufacturing processes and operational workflows.

Core Capabilities

• Tackle day-to-day operational issues, diagnosing root causes and coordinating timely resolutions with teams.

• Direct and coordinate team activities to maintain smooth manufacturing routines and meet daily production targets.

• Uphold safety, quality and regulatory standards through rigorous adherence to procedures and incident response.

• Influence management on key process decisions, acting as change agent to drive improvements across operations.

• Demonstrate disciplined adherence to established routines while identifying opportunities for disciplined process enhancements.

Preferred Capabilities

• Familiarity with end-to-end manufacturing processes to own and optimize routines.

• Exposure to SOP drafting and revision to support consistent operations.

• Experience using data insights to monitor process performance and inform improvements.

• Understanding of instrumentation and measurement for process verification and control.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $36.77 - $61.35

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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