Senior Director, Epidemiology, Pediatric Vaccine-Preventable Disease

AstraZeneca seeks an outstanding candidate with in-depth, specialist knowledge of epidemiology and infectious diseases and their application to pharmaceutical development and medical strategy. The Senior Director will generate, evaluate, and present high-quality epidemiologic and clinical evidence to guide product value, risk–benefit, and appropriate use. They will offer scientific input to cross-functional decision makers and external bodies. They will stay expert in pathogen trends, surveillance techniques, and new therapeutic resistance. They will guide staff members, advisors, and contractors to finish critical tasks. They will mentor epidemiology and medical personnel. They will maintain awareness of the external environment to evaluate emerging health risks and prospects to protect populations worldwide.

Job Accountabilities:

• Evaluates and analyzes surveillance, clinical, and real-world data and generates high-quality epidemiologic input to the target product profile, medical strategy, value demonstration plan, and market access & pricing strategy for antibacterial and anti-infective products.

• Leads medical and epidemiologic contributions to research planning and resolves complex issues affecting clinical development.

• Leads AstraZeneca personnel, consultants and contracted specialists in building and management of diverse study types and related critical work.

• Collaborate with study team personnel and colleagues in development and administration of observational studies, registries, burden-of-illness analyses, and modeling (e.g., transmission dynamics, resistance evolution, cost-effectiveness of stewardship and interventions).

• Prepares proposals for epidemiology, RWE, and outcomes research work packages; manages vendor/CRO selection and oversight for surveillance studies, prospective cohorts, and data-linkage projects.

• Holds budgeting responsibility for subprojects within medical, value demonstration, or clinical program teams; ensures delivery to time, budget, and quality.

• Leads project management with academic partners, public health agencies, and CROs; contributes to investigator meetings and prepares scientific work materials and presentations.

• Assists in medical writing, references, and development of dossiers and evidentiary materials for reimbursement/formulary decisions; ensures integration of epidemiologic burden and unmet need.

• Prepares epidemiology and outcomes evidence as background materials for regulatory submissions and interactions; participates in regulatory discussions on clinical development, labeling, and post-marketing commitments (e.g., surveillance plans, pharmacovigilance, efficiency in subpopulations).

• Advances knowledge of infectious-disease epidemiology and the impact of pharmaceutical product development; identifies and curates external data sources (national surveillance, hospital networks, lab databases) and literature to inform strategy.

• Reviews independent investigator proposals to incorporate relevant epidemiologic and outcomes components consistent with local clinical development and Phase IV/post-marketing requirements, including stewardship outcomes.

• Builds a culture of curious leadership, scientific rigor, creativity, and teamwork; champions public health priorities; leads reporting team members to success in project design and execution; develops professional growth among reports.

Essential

• MD or PhD in a relevant field (epidemiology, infectious disease, public health, health services research) with a minimum of 10 years experience within the pharmaceutical, medical, and/or public health sector(s)

• Demonstrated excellence in leadership.

Desirable

• Knowledge of international healthcare systems and their evolving needs for epidemiology, outcomes, and stewardship evidence.

• Strong knowledge of legal/regulatory environments influencing clinical research, product labeling, promotional claims, and appropriate-use programs.

• Ability to provide innovative scientific leadership across medical strategy and value demonstration work streams.

• Evaluate threats and opportunities and adapt strategy accordingly.

• Developed conceptual and analytical thinking, with access to internal/external expert resources.

• Implement projects with high autonomy

• Communicate medical strategy, epidemiologic evidence, and value narratives to commercial collaborators.

• Developed cultural sensitivity and the ability to represent the company externally to key scientific and public health partners.

The annual base pay for this position ranges from $229,047.20 - $343,570.80. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

When we put unexpected teams in the same room, we ignite ambitious thinking with the power to inspire life-changing medicines! In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting flexibility.

Join us in our outstanding and ambitious world!

Why AstraZeneca:

Here, courage, curiosity, and collaboration fuel a relentless focus on transforming cancer outcomes, powered by a pipeline that fuses ground breaking science with advanced technology. You will work in an environment where unexpected teams come together to fuel bold ideas, backed by meaningful investment and a clear path from discovery to impact. We value kindness alongside ambition, and we empower leaders at every level to ask sharp questions, take smart risks, and turn data into decisions that help patients sooner.

Date Posted 21-Sep-2026

Closing Date 28-Sep-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.