Production Technician I/II/II- Nights

Our Frederick Manufacturing Center (FMC) creates life-changing medicines for people around the world and has been recognized by our local community as being a Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’. This distinctive biologic manufacturing facility, with over 800 employees, makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe. We work hard to deliver life-changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team-building functions, we take time to recognize our achievements and celebrate our diversity. We are dedicated to creating a culture of inclusion and collaboration and are committed to continuous learning by offering ongoing skill building and training for our staff. Fueled by our aspiration to deliver accelerated growth for our company and to make people’s lives better, there’s never been a more exciting time to join the team and shape the future of AstraZeneca Operations.

Are you ready to break new ground and leave a collective legacy? As a Production Technician I at AstraZeneca, you will have the opportunity to play a pivotal role in evolving our Supply Chain. You will be operating upstream / downstream / central services processing equipment according to established SOPs. This is your chance to be part of a team that's reimagining how we do things and creating a collective legacy.

This role is 12 hour rotating night shift, 6PM to 6:30 AM

The facilities:

The center operates 24/7 with multiple shift schedules. We have dedicated employee teams who encourage site engagement passionate about community outreach, environmental issues, health and wellness, and site activities/events!

Job Responsibilities (this list is not exhaustive):

• Operation of processing equipment according to established SOPs, MPRs, & SPRs in accordance with cGMPs. Related operations include but are not limited to solution preparation, cell culture, purification & formulation, and supporting activities.

• Qualified on the floor trainer.

• Demonstrates sophisticated equipment/process knowledge to diagnose issues and participate in first-line troubleshooting and root cause analysis.

• Follow and implement cGMP documentation.

• Maintain qualifications in Production Technician duties

• Use Manufacturing Execution systems (MES).

• Complete work orders within system.

• Support SOP updates.

• Contributes proactively to problem solving activities for non-routine activities on production floor.

• Perform duties with basic direction.

• Lead indirect processing activities in support of MFG operations.

• Lead continuous improvement initiatives.

• Align with AstraZeneca values and behaviors.

Minimum Qualifications:

• Tech I: High School Diploma/GED +1 year experience in a pharmaceutical/ biopharma environment

• Tech II: High School Diploma/GED +2 years' experience in a pharmaceutical/ biopharma environment

• Tech III: High School Diploma/GED +3 years' experience in a pharmaceutical/ biopharma environment

Desirable Qualifications:

• BS/BA degree

• Degree in STEM field

• Ability to work independently or in collaboration with others on assigned tasks

• Computer skills

• Prior experience with aseptic/cGMP standards

• Extensive prior experience in Bioprocessing work environment/ systems/ equipment operation

Be part of crafting the future of Operations here at AstraZeneca!

Build on our foundations of dedication through agility, responsiveness, reliability and efficiency, to deliver our new modalities and refined pipeline to market at speed. Backed by an encouraging team, be part of accelerating our operational excellence with innovations in ground breaking science, Lean ways of working and ever-evolving digital technologies.

The annual base salary for this position ranges from $59,744 - $89,616 annually. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

AstraZeneca is where science meets innovation to create impactful solutions! We challenge the status quo by leveraging data to drive scientific breakthroughs that make a tangible difference in patients' lives. Our collaborative environment fosters learning and growth, empowering you to contribute to meaningful research across global Therapy Areas. With countless opportunities for development, AstraZeneca is committed to investing in technology and expanding knowledge to maximize impact.

Ready to make a difference? Apply now to join our team and be part of something extraordinary!

Date Posted

17-Sep-2026

Closing Date

30-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.