Senior Director, Global Clinical Development, Neuroscience

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The Senior Director Global Clinical Development, Neuroscience will be the main point of contact to prepare the clinical development plan, design clinical trials and lead the clinical development teams. Extensive experience in clinical development of neurodegenerative and/or neuropsychiatric indications is a requirement. Demonstrated expertise in basic research related to neurodegeneration and/or neuropsychiatry is a plus.

The Neuroscience Clinical Development function is part of a global scientific organization dedicated to initial evaluations of new molecules, biomarkers, and mechanistic hypotheses in humans. The group drives clinical strategy, and the design, execution, and interpretation of studies to select the most promising drug candidates for development.

Position Summary / Objective

• Serve as the clinical point of accountability for the Clinical Development Team and responsible for the overall clinical development plan for asset(s) in one or more indication(s)

• Demonstrate matrix leadership to develop, motivate and achieve results through teams; enable development of a resilient attitude, embrace change and have an unwavering commitment to organizational People Strategy

• Ensure studies are designed to meet regulatory, quality, medical, and access goals

Position Responsibilities

Medical Monitoring

• Serves as an independent Medical Monitor for clinical trials by

  • Articulating clinical development strategy
  • Analyzing, interpreting, and acting on clinical trial data towards development
  • Serving as principal functional author for Regulatory submissions, study reports, and publications

• Independently synthesizes and/or contributes to plans (e.g., trial design, development strategy, regulatory strategy) based on merging data and multi-functional input

• Designs and develops clinical studies and research plans in support of asset strategy with the program and clinical development teams

Clinical Development Expertise & Strategy

• Manages multiple/complex active programs concurrently across clinical lifecycles

• Accountable for clinical contribution to the development of indication strategy

• Partners with Worldwide Patient Safety physicians in the ongoing review of safety data

• Provides clinical leadership and disease area expertise into integrated disease area strategies

• Partners closely with KOLs in specific indications

• Evaluates strategic options against a given Target Product Profile (TPP)

• Collaborates with Global Development Operations/Global Compliance Group to develop asset level risk management plan, resolves issues with Quality/Clinical Scientists, and raises to Clinical Development Team as needed

• Sets executional priorities and partners with Clinical Scientists to support executional delivery of studies

• Accountable for top line data with support of Clinical Scientists and Statisticians

• Liaises with Clinical Scientists, Translational & Discovery Scientists, and Development Teams to define dose and schedule, indications, and patient selection (e.g., biomarker qualification and implementation)

• Liaises with other functions (e.g., Thematic Research Centers and Translational Medicine) and apply foresight and prioritize translational objectives in anticipation of development needs

• Ad-Hoc involvement in various departmental or enterprise initiatives (e.g., committees, sub-teams etc.)

• Presents and/or articulates clinical strategy to senior leadership and to support progression of portfolio

Health Authority Interactions

• Serves as primary clinical representative in regulatory interactions

• Accountable for clinical contributions to clinical study reports (CSRs), regulatory reports, briefing books and submission documents

External Partnerships, Alliances, and Publications

• Acts as a focal point for defining and establishing relationships with key investigators

• Sits in team responsible for establishing key alliances with academic centers, co-operative groups, vendors and government agencies

• Represents department in business development due diligence and partner alliance management as appropriate; sits on JDC/JRC/JSC as appropriate

• Track record or recognized for contributions to field (e.g., publications, patents, keynote participation in conferences etc.)

Leadership and Matrix Management

• May be responsible for managing Clinical Trial Physicians and Clinical Scientists, attracting, developing and retaining top talent; ensures appropriate training and mentoring of other physicians and scientists

• Champions a quality-focused mindset and ensures adherence to GCP and compliance obligations for clinical conduct

Degree Requirements

• Advanced degree(s) in relevant field: MD or MD/PhD and deep clinical expertise in a therapeutic area

• Fellowship/specialty training in relevant therapeutic area preferred

Experience Requirements

• 7+ years of relevant experience in discovery, translational and/or clinical research in academic or industry setting

• Extensive experience in clinical trial design and execution, biomarker development, and development strategy in pharmaceutical industry

• Deep understanding of pharmaceutical discovery, development and commercialization

• Track record of mentorship and/or management and/or matrix leadership

• Demonstrated leadership abilities in a matrix environment

Key Competency Requirements

• Excellent skills in clinical development strategy including the clinical components of regulatory submission(s)

• External focus to understand the trends in the disease area treatment paradigms and ability to build relationships with external partners, thought leaders and collaborators outside of BMS

• Partner and interact with colleagues from across the development lifecycle

Travel Required

• Domestic and International travel may be required

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview: Cambridge Crossing: $350,780 - $425,060 Madison - Giralda - NJ - US: $313,200 - $379,524 Princeton - NJ - US: $313,200 - $379,524

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include: Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodations/adjustments prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1604864 : Senior Director, Global Clinical Development, Neuroscience