Director, Obesity Early Pipeline Commercial Development

ROLE SUMMARY

Obesity is one of the most exciting and dynamic areas in medicine today, and Pfizer's early obesity pipeline spans multiple mechanisms with the potential to help hundreds of millions of people living with obesity and its complications worldwide. The pace of scientific and competitive change in this space is unprecedented, creating a unique opportunity for a commercial leader to shape assets from their earliest stages.

The Director, Obesity Early Pipeline Commercial Development sits on the Obesity Global Commercial Strategy team within the Internal Medicine / Primary Care business unit, reporting to the Senior Director – Team Lead, Obesity Early Pipeline Commercial Development. The role is accountable for commercial development across a portfolio of early- and mid-stage assets spanning the chronic weight management treatment landscape. The Director owns commercial assessments end-to-end for covered programs — building product concepts and Target Product Profiles, developing disease-area strategies, and directing the integration of forecasting, pricing, HCP demand, future landscaping, and patient-flow insights into actionable commercial plans.

Operating as a cross-functional leader without direct line authority, the Director interprets business unit strategy to set priorities for covered programs, shapes early development strategy in partnership with R&D, advances assets through enterprise governance, and leads select strategic initiatives spanning the broader obesity portfolio. The role requires a strong sense of urgency, comfort operating in ambiguity and white space, the ability to translate emerging science and market signals into investment cases, and a regular cadence of engagement with senior leadership. The Director may manage consultants, growth gigs, etc. in support of these objectives.

ROLE RESPONSIBILITIES

• Own end-to-end commercial assessments for a portfolio of early- and mid-stage assets across the chronic weight management treatment landscape, spanning multiple mechanisms and stages of development.

• Build product concepts and Target Product Profiles for covered programs; develop and maintain disease-area strategies that position each asset within the evolving treatment landscape.

• Shape early development strategy in partnership with clinical and research colleagues, ensuring commercial considerations inform candidate and program design.

• Interpret business unit and obesity franchise strategy to establish priorities and longer-term direction for covered programs.

• Direct the integration of forecasting, pricing, HCP demand, future landscaping, and patient-flow modeling into actionable commercial plans, partnering with insights, analytics, finance, and medical colleagues.

• Support development of core global asset deliverables, ensuring alignment with clinical profile, customer insights, and competitive positioning.

• Anticipate external market, competitive, and policy developments affecting the obesity landscape, and adapt asset strategies accordingly.

• Evaluate and prioritize lifecycle management and expansion opportunities for emerging assets, including new indications, populations, and access pathways; develop business cases and scenario analyses that inform expansion investment decisions.

• Support business development evaluations and due diligence as needed.

• Lead select strategic initiatives spanning the broader obesity portfolio, including exploratory strategic areas and emerging access models.

• Advance assets through enterprise governance milestones, owning preparation and delivery of asset-level governance materials.

• Present asset-level and above-asset strategy and investment cases to senior leadership; influence decisions on portfolio direction, prioritization, and resourcing.

• Mobilize cross-functional resources beyond direct authority; may manage consultants and agency partners.

• Champion innovation and appropriate risk-taking in approaching novel commercial questions; share knowledge, insights, and best practices across the commercial development organization.

BASIC QUALIFICATIONS

• BA/BS required.

• Minimum 8 years of pharmaceutical, biotechnology, healthcare, or related industry experience.

• Experience in commercial development, new product planning, marketing, portfolio strategy, or related strategy roles.

• Proven experience leveraging AI to enhance robustness of work deliverables and speed of delivery.

• Knowledge of obesity, cardiometabolic, or related therapeutic areas.

• Familiarity with the pharmaceutical development process.

• Familiarity with the Regulatory process for drug approvals.

• Demonstrated ability to execute effectively in highly dynamic and evolving markets.

• Strong analytical skills.

• Ability to communicate complex information clearly and succinctly.

PREFERRED QUALIFICATIONS

• Advanced degree (MBA, PharmD, PhD, MD, MPH, or equivalent) preferred.

• Advanced scientific and business acumen with experience in obesity or metabolic disease.

• Experience supporting early-stage development assets and development strategy.

• Experience collaborating with R&D and Commercial cross-functional partners (e.g., IIS, CI, GAV, GMA, PDA, etc.).

• Experience with the execution of market research.

• Experience developing forecasts, asset valuations, business cases, and scenario analyses.

• Experience supporting business development assessments or due diligence.

• Experience preparing and presenting strategic recommendations to senior leadership or governance forums.

• Demonstrated ability to lead and influence cross-functional teams without direct line authority.

PHYSICAL/MENTAL REQUIREMENTS

• Ability to analyze complex clinical, commercial, and financial data sets and translate findings into strategic recommendations.

• Ability to manage multiple priorities, changing business needs, and significant ambiguity while maintaining high-quality decision making.

• Ability to participate in extended strategic planning, governance, and operational review meetings.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Domestic and international travel up to approximately 10–20%, based on business needs.

• May require participation in meetings outside standard business hours to accommodate global stakeholders.

LAST DAY TO APPLY: 08/17/2026

The annual base salary for this position ranges from $162,900.00 to $271,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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